The Prevalence of Female Pattern Hair Loss in Postmenopausal Women

The Prevalence of Female Pattern Hair Loss in Postmenopausal Women

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Greater than half of postmenopausal girls ages 50 to 65 years have feminine sample hair loss (FPHL), and low vanity is related to extreme FPHL, in line with findings from a research revealed in Menopause.

Researchers sought to estimate the prevalence of FPHL in wholesome postmenopausal girls and decide the postmenopausal hair traits and elements related to FPHL.

The cross-sectional research enrolled postmenopausal girls aged 50 to 65 years with a 12-month historical past of amenorrhea or oophorectomy from a Menopause Clinic in Bangkok, Thailand, from November 2018 to Might 2019.


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FPHL was analyzed in line with the Ludwig classification. Hair density and diameter had been measured with trichoscopy, and scalp sebum was measured with sebumetry. Low vanity severity was assessed in line with responses on a questionnaire. A prognosis of FPHL was confirmed when 3 dermatologists with particular curiosity in trichology reached an settlement.

A complete of 200 postmenopausal girls had been initially enrolled, of whom 178 had been assessed for his or her attribute hair patterns. Contributors had a mean age of 58.8 ± 4.1 years and a mean time since menopause of 9.2 ± 5.6 years. A complete of 82% of the ladies had by no means used menopausal hormone remedy (MHT), and 5% had been utilizing MHT.

The cohort had an FPHL prevalence of 52.2% (95% CI, 44.6-59.8). After stratification in line with age and time since menopause, the prevalence of FPHL elevated as the ladies’s age progressed. Ludwig grades I, II, and III percentages had been 73.2% (95% CI, 62.9-81.8), 22.6% (95% CI, 14.6-32.4), and 4.3% (95% CI, 1.2-10.7), respectively. About 60% of the ladies had been decided to have low vanity, which elevated with the severity of FPHL. All girls with Ludwig grade III hair loss severity had low vanity.

Age 56 years or older (OR = 3.41, 95% CI, 1.67-6.97), time since menopause of greater than 6 years (OR = 1.98, 95% CI, 1.03-3.83), and physique mass index (BMI) of 25 kg/m2 or larger (OR = 2.28, 95% CI, 1.11-4.66) had been all considerably related to FPHL within the girls, in line with easy logistic regression evaluation.

Multivariable logistic regression evaluation after adjustment for age and household historical past of FPHL in 1 mannequin confirmed that solely BMI 25 kg/m2 or larger was considerably related to FPHL in postmenopausal girls (adjusted OR = 2.65; 95% CI, 1.23-5.70). After adjustment for time since menopause and household historical past of FPHL, a second mannequin additionally indicated {that a} BMI of 25 kg/m2 or larger was considerably related to FPHL within the girls (adjusted OR = 2.48; 95% CI, 1.18-5.20).

Research limitations embrace the cross-sectional design and comfort sampling performed at a menopause clinic, and ladies who underwent hair loss therapy had been excluded. Most knowledge had been collected primarily based on the contributors’ reminiscence, and one-third of the ladies had serum testosterone ranges decrease than the assay limits.

“Excessive BMI or weight problems was related to the next prevalence and worsening of FPHL in postmenopausal girls,” acknowledged the research authors. “Additional research are needed to find out whether or not intercourse steroid hormones, particularly estrogen and testosterone, and historical past of polycystic ovary syndrome are associated to hair loss in postmenopausal girls. This may occasionally assist gynecologists choose applicable menopausal hormone remedy regimens for postmenopausal girls with FPHL.”

Reference

Chaikittisilpa S, Rattanasirisin N, Panchaprateep R, et al. Prevalence of female pattern hair loss in postmenopausal women: a cross-sectional study. Menopause. Revealed on-line February 14, 2022. doi:10.1097/GME.0000000000001927

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