And now here is a question. Why is this pattern of hair loss only in the front and on top? That’s where ‘hormonesensitive’ follicles live. These ‘self renewing’ cells divide, when they get the right set of chemical signals. They don’t divide like normal cells, in which both halves become new cells that split and developing.
Only one the follicle half stem cell does that. That’s where follicle stem cells live. Alopcia areata ain’t associated with a more serious condition known as cicatricial alopecia, in which the health attacks the stem cells in the bulge of the folicle. One after effects of Propecia can be loss of libido. Those new treatments aren’t nearly ready for prime time, like the cure for cancer. So Holy Grail of hairloss treatment is getting shutdown follicles to regenerate. Nonetheless, that’s what Cotsarelis’s lab is working on. Already they’ve made a major breakthrough. Similarly out of fashion are flap type procedures, where a flap of hair from a hairbearing area is partially removed, swung around, and attached to a frontal area. So result. I know that the anagen stage of hair growth gets shorter, and the resting stage gets longer.
What’s clear is that similar thing happens in aging men and women. Hair follicles get smaller. There’re good reasons this kind of technology will move forward. Today, Americans spend $ 800 million on hair restoration surgery.
Consequently, So it’s, if this all sounds futuristic. Aging women have a similar problem. Notice that it keeps the male sex hormone testosterone from forming its DHT byproduct. It works only for men. Why? Actually the other currently approved drug for hair loss is Propecia. Hair follicles live just below the top layer of the skin. Plenty of us, when we think of hair loss, think about aging men. Fact, nearly all men eventually get that receding Mshaped hairline and thinning hair on the top of the head, and known as male pattern baldness.