Hair Loss – This Agent Is A 5 Alpha Reductase Antagonist

Finasteride is also used for Female Pattern Hair Loss.

Why this is so, is still being determined scientifically. The optimal effect is at a much higher dose than what is used in men. On p of this, hundreds of these agents are anti androgen or anti male hormone, HOWEVER, most women with Female Pattern Hair Loss have been found to not have excessive male hormones. Basically, this therefore blocks dihydrotesterone formation from testosterone, stopping more potent androgen from acting on hair follicle. Fact, like with men, it takes about 4 months to see tobenefit. While women typically have four major agents available, men only have Finasteride available for use. Furthermore, interest thing however, is that they still respond to these use agents. This agent is a 5 alpha reductase antagonist. With that said, this medical management of Female Pattern Hair Loss is has many more options forwomen.

Spironolactone is a ‘antihypertensive’ diuretic aka a water pill that promotes loss of Sodium in urine to help aid in dropping Blood Pressure. It is used more in pre menopausal women. It is used more in women with an underlying cause of Female Pattern Hair Loss such as Polycystic Ovarian Syndrome. As a result, it takes 4 months to see any difference. It, at a low dose had been used for this indication in both men and women for nearly 50 years. At much higher doses, it has ‘antimale’ hormone effects. It can reduce body hair on chin and chest BUT it increases hair growth on tohead.

This is another anti male hormone medication that was used in ‘pre menopausal’ women.

It is present in low doses in certain contraceptive pills such as Diane 35 which is found in many countries apart from United States. Women can be poorer candidates than men because their hair loss tends to cover a much larger area from very early. Keep reading! Hopefully hair cloning gonna be successful and gonna be available in tofuture. These hairs will have to be addressed using some sort of medical management or person will have to end up doing more than one hair transplant in their lifetime. Then again, sufferers of FPHL can also benefit from hair transplantation, like with Male Pattern Hair Loss. It is a bit of a successful operation as more than 95% of transplanted hairs will grow and stay. Actually, women are advised not to get pregnant whilst taking tomedication. Let me tell you something. For effective control of hair loss, Androcur is used because it is at a higher dose. Needless to say, main problem is that original hairs surrounding transplanted hairs are still being affected by Female Pattern Hair Loss.

This is another 5 alpha reductase inhibitor. This is another antiandrogen medication that is available in medication arsenal for Female Pattern Hair Loss. Most use this as a last resort. It is more potent as a ‘anti androgen’ as it acts on two enzyme forms that converts testosterone to dihydrotestosterone. Yes, that’s right! Time to see a difference is up to 4 medication using months continuously. The problem with this medicaiton is that it can cause severe liver toxicity. Essentially, it is a newer agent that is use ‘off label’ mainly for ‘post menopausal’ women as it stays in body for a much longer time than Finasteride.

FPHL is treated with agent Minoxidil, like Male Pattern Hair Loss. Like with Male Pattern Hair Loss, it takes 46 months with continuous use, to see tobenefits. It is best to decrease dosing to once a day or once alternate day, with intention to combat this. The dose recommended for women is to2% solution used twice daily or to5% foam once daily. The real problem lies in amidst to consequences which is excessive hair growth. It is more likely to occur in women and with 5percent concentration used twice daily. Most hair loss experts like to use to5% solution or foam twice a day as it just seems to work better, with intention to be honest.

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