Results of the study showed that all 3 shampoos got rid of itching and dandruff quickly. Ketoconazole is a member of the azole antifungal agents. By its ‘fat soluble’ nature, ketoconazole can be easily absorbed into fatty tissues where it can accumulate. Redish No. So this shampoo product has a redorange color and it suspends the active ingredient in a mixture of these inactive ingredients. Regarding tinea versicolor, Nizoral is active against the fungus, Pityrosporum orbiculare also known as Malassezia furfur. Ketoconazole has a direct ‘anti inflammatory’ property that can ketoconazole permeating the scalp from Nizoral shampoo can block the androgen receptors found in hair follicle cells. Fact, ketoconazole is an antagonist at these receptors. Did you know that the second mechanism is the inhibition of androgen receptors. Other reported adverse reactions of Nizoral shampoo include rash, itching, contact dermatitis, dry skin and burning sensations. Did you know that the researchers repeated this experiment and achieved quite similar results.
Besides fungal infections, ketoconazole is also used to treat other medical conditions because of some amount of its desirable aftereffect. Amid the consequences of ketoconazole is the suppression of testosterone. It involves the conversion of testosterone to DHT in hair follicles. Oftentimes androgenetic alopecia is the most common type of hair loss. Then, very little of Nizoral is absorbed through the skin, if applied to the skin surface. Risk of systemic toxicity is very low. Nizoral does not become toxic or trigger allergic reactions on the skin on exposure to sunlight. Remember, by turning down the secretion of sebum from the sebaceous glands attached to the hair follicles, ketoconazole prevents the skin pores of the scalp from clogging up. Of course safety studies on Nizoral are inconclusive or lacking.
Pregnant women should only use the shampoo when the benefits outweigh the risks. So superiority of the combination of finasteride and ketoconazole was further confirmed by a 2004 study published in the journal, Medical Hypotheses. Generally, the active ingredient of Nizoral, ketoconazole, acts by disrupting the cell membranes of fungi. Even at high doses, oral ketoconazole can’t effectively block androgen receptors. It’s secondary mechanism for the effectiveness of oral ketoconazole pills. Did you know that the results showed that both 2percent ketoconazole and 2 minoxidil were effective for stimulating hair growth. With that said, this study further proves that ketoconazole even at 1 concentration can provide some benefits for people experiencing hair loss. Doesn’t it sound familiar? This study showed that ketoconazole shampoo ranks high amongst the drug used for treating androgenetic alopecia.