Hair growth can resume at any point spontaneously, the condition doesn’t kill the hair follicles, and in it’s in your best interest to communicate that clearly to her/him that a completely different treatment plan can be discussed, I’d say if you are not preparing to use what your dermatologist is prescribing for you.
The prescribed cortisone cream in this case, you may look for to consider doing so, if you have not already talked with your dermatologist about your reluctance to use medication usually. Cortisone is used in cases of alopecia to stimulate hair growth in the position where it’s injected or applied topically. Essentially, taking care of you is a combined effort between you and your health care provider, and clear and open communication will result in better treatment. What I like a lot about Christiano’s approach is she focuses on the genetics behind it.
Specifically one of these SNP’s has something like ^-89, that is the single most at risk SNP amongst Europeans.
Both AA and AGA are highly hereditible.
Number 2 at risk spot is 20p11 and its SNP’ One SNP from this set has ^-39, the second most at risk SNP in the genome. We already know that the set of SNP’s between EDA2R and AR confers the most risk for Europeans for AGA. Study the genes to find the answers. Then, would like to hear how those products work together, specifically the dermarolling bit.
I am sick of waiting for these drug companies and am planning to start testing products on myself, as well.
Thanks. At some point I might ban them….wish I could just limit comments from such people to 3 per person per day max or something like that. Lol thanks danitello! A well-known fact that is. Mostly there’re just ’23’ regular posters who are mostly posting garbage. I need to hire a programmer for that. Another question isSo the question is this. What if they do come up with an awesome solution and you stripped off a big strip of follicles off the back of your head?
Your dad’s and forefather’s should kick your asses if they knew that a certain amount you wanted to give up on life because of a genetic curve ball life through at you.
That is just life.
You are intending to wish you waited. Bottom line is this. I have said this a lot. You are preparing to continue to get women, So if you got women before. Now regarding the aforementioned fact… For you guys that say that it’s not about women, thence you need to learn to like yourself for other reasons than your hair. I use Minoxidil, I think I’m 4 months in. They will always go, it just makes those hair cells do more., right? DHT did it’s job. I haven’t noticed any improvement or thickening of the hair. Please explain this to our teenage mutant ninja turtle MR Donitello who had been putting his nose in every reply as if someone has asked him about his opinion.
What are you doing here, man?
If they could, the boards are littered with people who all say that they should go back and not have the procedure.
It’s top-notch case scenario. Not one. Nevertheless, if you are lucky, you have locked yourself into ’30 50′ years of misery. Yes, that’s right! Transplant is not going to stop it. Worst case, you have a botched procedure and you are ashamed to leave for awhile being that the world has a clear picture of your insecurity and you are disfigured. You might be spending close to $ 30- $ 40000 by the time you die. Oftentimes do some looking around on the various forums. After the initial $ 10000 surgery, you will have to get uch ups done. I haven’t for awhileterm reviews on minox. Think of all the things you could’ve done with that money? Not everyone can use FIN. I have yet to see someone who got a hair transplant be thankful for having had one done 20 years later. Fact, instead, you spent it on your insecurity. Same with HT. Baldness keeps going. With all that said… It is a smooth muscle, and stat3 mRNA and protein is expressed in both smooth and striated muscle types so perhaps this could work.
Perhaps inhibiting AR/stat3/il 6 will bring about the repair of the arector pili muscle.
WE ALREADY KNOW that it’s possible for arector pili to regenerate under the right circumstances.
Therefore this suggests to me that the for a while because being since the hair follicles themselves and not the other way around. Aka non stat3/AR/il6″ dependent hair. Attenuating this allows muscles to be repaired when JAK/Stat signaling gets basically it went to trials and no trace. Look what they can do for chicks with small boobs…exactly like that we men need a better cosmetic option.
For lot of people its just a joke, I’d say in case baldness was a medical emergency it will have been cured by now.
All the other companies are just commercial and hiring my be great atleast if they can create a proper cosmetic option which is semi or tally permanent and doesnt need maintenance like toupee. We baldies are not going anywhere, everyday the technology and research in other fields is growing. Therefore if a proper scientist looks into this matter will have been cured by now, honestly I reckon the main stream people dont give a shit about baldness. Bloody baldness is a joke anyways, few cures that might work will give you what impotency. Usually, I was really excited when JAK news came up but now I dont think they are doing anything about that. Normally, people with AA always have the off chance that their hair will just grow back. Then, everyone actually is focusing on alopecia areata first, that I don’t understand why.
Plus even they have better treatment options than we do.
The market for mpb is HUGE!
It seems like mpb is not a very serious or pressing concern to any scientists doctors.
Cb does not. It must be cheaper in the future. Ru and Fin give sides. Anyways, if I had more hair I can better pull off having a big nose. Damn! I honestly feel like ill look like a weird dude when I have my head shaved with big ears and big nose. Guys I know this isnt about hair I but where must I go to get opinion on if my nose is look for the publics opinion on my nose but dont look for to put my mug shot online. Yes they have been naked, thence my conclusion is we must go back in time, and that mean we all go naked again.
First men had hair all over the body, now 60000 years later all hair is gone, the question is why, evolution?
That’s literally similar press release from April 1st.
That news source is behind. However, the hair specific work will probably be commercialized in about 6 or 7 years. Therefore this has nothing to do with his hair follicle germ work. Let me tell you something. They are independent operations under identical regenerative medicine division. Then, I think a bunch of us here agree on the main culprits being the disintegration of the comments sections. You should take this seriously. Now, a couple of losers who have nothing else to do in their lives.-) I hope you pick identical culprit names as I do mjones!
So interesting thing is that dr Tsuji does not answer on ’emails’ about hair regeneration.
That’s a fact, it’s suspicious.
Please dont tell me that he is busy because of skin development. He is probably getting annoyed that 5000 people email him daily about a treatment he is not trying to solve. He is focusing on skin guys and luckily hair follicles are on skin. If you plan to scalp yourself and put new skin thence tsuji might be your guy. He doesn’t give a sht about us. You see, everyone has their own problems and in my opinion hair loss is nothing when put in perspective we live in an incredible era with very promising technology that will enable us to achieve things we could not even dream of! No one except would be posting here, everybody could get a FUE HT, if current medicine will provide maintainance from the moment we spotted our hair loss.
One thing that technology won’t be able to do is give you back the time you wasted despairing on your hair loss.
That is absolutely ridiculous.
He is aiming for human trials in After that there might be about 3 or 4 years till commercialization. I’m disappointed in you Lewandowski for even entertaining the thought that it would for a while. You guys are speaking with your emotions. Certainly, most welcome bigger than the cancer market, do you know what percentage of people get cancer in their lifetimes? It is keep to the post or dont comment, its insane and almost impossible to even bother to read to find a legit comment. That’s interesting. What it does to your life?…and usually results in a terrible death. Why are their so many comments about random craap on here? We are in an age where we deserve yes or no answers. I give him till July to post proof that his lotion can grow hair for aga. With that said, this goes for jak as well. Generally, if not only sell it for AA and stop messing with our heads.
No more bsing us.
Admin in my opinion you must close for ages as it’s turning worse than my conspiracy theories haha.
Tired of these false hopes. Certainly, just use the shit on a mpb man for 6 months take the fking pics and post it online so you can prove it’s success. Although, wow this blog has gone to shit fast lol. Generally, you have your answer that it doesn’t work, if he doesn’t or pulls some sht that it needs further testing. Now look. The main thing I will add to this which I find shady is that brontzu claims that his lotion works for aga yet he doesn’t show any pictures of it, only AA. Did you hear of something like that before? While discontinuing them, my opinion about why this hasn’t been solved for any longer being that the endeavors to find a cure are not focused enough, they are will simply collapse allowing the necessity of doing better treatments.
HT industry is worth 800 Million a year and only in the US… so it’s guaranteed per year.
Why chemo and radio are better for cancer?! It’s in your for any longer being that it’s the main tx they sell.a lot. We need to keep positive, true but, not believing in any bs that comes out giving hopes that should be in 5 10 or gazillion yrs… Ideally everyone should stop using minoxidil. It would just be nice to know if there was a light right after the tunnel. Id be ok for awhile being that for those five years I could try to maintain, or even rock a hair system a couple years before I finally did take it. You always see these articles on how a completely new drug is the potential cure, therefore it goes away and you don’t hear about it for ages. Its this not knowing BS that sucks. Like even to hear, we wont release it for 5 years, yes Jak works and regrows back a NW2 hairline in months. On p of this, message to all scientists, spokespersons and others.
It would’ve been nice to stop doing meetings and give to all of you a safer and more effective treatments than current treatments. They really deserve it. I think they are making an attempt to make their own jak lotion as they can’t use pzifer made ones…. It’s expensive too… Dude no company can buy a possible cure bcos they don’t make that much money. Known say if jak works nearly any one will start using it… People who are using current treatments are like 2percentage of the hair loss sufferers… no company is rich enough to pay a cure. Essentially, even if they are they will buy the cure and release themselves.
Jak will work for sure.
It’s been done they need to just combine them and make a topical….
Matt these jak drugs are already fda aproved, you even wrote that in your comment. Use this twice daily with once daily finasteride. Just like propecia was prescribed to men off label before becoming official for AGA. Now pay attention please. I truly wish someone wealthy will go to a doctor and get a jak stat inhibitor prescribed off label. Also, spencer Kobran of the Bald Truth Talk specifically mentions this happening to him, and being fortunate to have it prescribed to him off label before it became mainstream. Take it to a pharmacy and have it compounded into a topical, of relatively high concentration. Nonetheless, is that feasible given the current state of research?
Would we not have at least Therefore if a cure was supposed to arrive by 2020.
This just doesn’t seem pragmatic, I’m almost sure I apologize if I have offended you.
You still believe it’s feasible for a cure to be released by the end of 2020, right? Generally, I do commend your efforts to spread positivity. Is it not a little reckon that this malady should be cured, I’m quite sure I understand you seek for to keep readers interested. I dont think after 40 years old I’ll be bothered, at the moment im in my prime where I just wanna style around and enjoy my youth but by 40 even if the cure was to come out I’d probably just leave it basic. Certainly, will be so uplifting and a confident booster to be able to change your hair, its incredible how different you can look and how much of a sex appeal it really is, its no wonder they use it very much for commercialism So in case you try for ageser than 3 to 6 months so write it for a whileer than that if you even get sides. That’s just my advice. Please do not listen to scare stories on forums. Therefore in case you don’t get on Propecia YOU WILL GO BALD. Get on Propecia ASAP to save what you have. I am currently 19 and both of my grandparents and great grandparents had hair but all of their male children don’ Which is unlucky for a while being that I have the balding genes and I’m loosing ground fast. I was just wondering if you guys can answer a few minoxidil questions for me. I refuse to accept being bald before my 30th birthday. I legitimately don’t know if I could be capable of enjoying things anywhere close to 100 percent if I become a chrome dome. I’m quite sure, that’s a reality that is completely unacceptable to me, I don’t care months worth runs $ 2000 or more.
Anything less than 1percentage Tofacitinib or Ruxolitinb will do nothing and Christiano said herself in the interview that it needs to be in a high local concentration to have the effect seen.
I think it can be done in the United States.
Only one FDA approved JAK inhibitor so far. I personally wouldn’t feel comfortable buying from Mexico but to every their own. It will just take a general practitioner willing to prescribe this to you for the purpose you need. Then, the mice were given 3percentage topical. I think you should only need ’13’ months worth to create a pical in the right percentage. A well-known fact that is. It will take someone knowledgable enough to create a pical with the JAK/stat inhibitor as the main ingredient that should stay in the epidermis/ dermis mainly. It has to go through the risk doesn’t outweigh the reward for the product test, when something does work.
I agree that regulations are look for your competitors to be right on your heals if you are right so you are releasing dated information to them.
Fact is when you live in a capitalist society with government regulations and a profit incentive, it means things can take a while. Although, you gotta hit both at similar time, and in high enough concentrations to change the micro environment of AGA effected hair. However, will this be reversible by targeting JAK/stat as well as AR at really similar time is the main question. By the way I doubt this is done yet as a high concentration pical JAK/Stat with proper for any longer enough time, in conjunction with heavily blocking AR via fin/dut to give the pical JAK/Stat some amount of time to work. You should take this seriously. If any of you had some expirience with that post pls.
Is anyone here tryed getting all his hormones tested and can it be that some ppl have hairloss due to low testosteron. I’m going I going to be a nwSucks that my hair is accelerating so fast after so many years of maintenence. You should think he will show regrowth pics for aga to boost popularity of his treatment. I am a little worried that he focused on showing it’s results for AA and nothing for aga. My gut is telling me this should be a bad sign. You guys think bronze lotion will work for mpb, right? Your AGA look, there’re different kinds of causes types on any persons AGA.
I get your frustration.
I think out of the maybe hundreds of bad AGA factors that maybe 3 or 4 are the root cause of all the others.
I think way more is known now about AGA and it is not just the simple DHT + bad AR = bald equation. It has just been a matter of finding which ones they are. Maybe you are right in the sense that it won’t be reversible without hair cloning technology. I think now they are closer than ever to pinpointing them. Of course, we are all frustrated. We have known that androgen is for a while. What we haven’t known is what are the other key players/interactions with androgenic hormones.
I thin k a few critical players are causing the entire phenotype.
I also don’t believe I know it’s as hard as some have suggested.
To suggest they are not close I believe is wrong. Khan telling me she has me on file and expect a call from the medical director, Yoda somehow surely is for awhile being that they contact him back immediately with before and after pictures and explained to him personally in his email how their procedure works. After months of them not contacting me through email or phone besides Dr. For instance, if anyone has questions about Thorn Medical get in contact for ages being that he is likely to be in really close communication with Thorn.
Im sure one of these treatment may be super efficient, to a point that it can make a nw7 has a head full of hair again, I’m pretty sure I suppose that nearly any possible future treatment about biomedicine gonna be expensive as hell.
Only the SNP’s at 20p11 are shared at risk spots amongst all people of all ethnicities.
Looking at FOXA2 functions on Wikipedia shows it to be involved in Androgen metabolism and response to ‘IL6’ amongst other things. FOXA2 and PAX1 are the genes on every side of the 20p11 SNP’s…. Therefore this tells me that IL6 and JAK/stat3 cascade and Androgens are what’s common amongst all people. Consequently, why Europeans start the earliest generally and have the highest incidence of AGA. Europeans just happened to evolve a couple of really nasty androgen receptor associated SNP’s that rapidly accelerates the inflammatory for a while. She knows something big and in my opinion she sold it off to that other company.
Imagine a pical that could tally reverse aga after 3 months.
I find it very shady and crooked.
Something is going on behind the scenes and it’s really pissing for awhile being that we all need our hair back and tired of waiting! Now this would destroy any hair loss drug, surgery, wig business. Online. That should get her more money and more attention that curing AA. So, I wouldn’t be surprised if jak actually cures aga and this other company is planning to shelve it and never say a word about it. For instance, it’s all shady bs! I still find it really weird she wouldn’t test it first for AGA. You should take it into account. It seems Iike AA, is more important than a blockbuster billion dollar discovery like aga cure. For example, starting in your late teens and early 20’s it can be a tremendously uch pill to swallow.
If this started for me when I was 50 I wouldn’t care nearly as much.
Well she does have a vested interest in AA first and for awhile being that it happened to her.
As much as AGA sucks, I do think AA would indeed be worse. It really is only truly terrible for those who start going noticeably bald at a very young age. Your youth is out of the way. AGA is still normal hair loss. I will monitor my progress with pictures and so I will definitely be able to judge the effectiveness. So, mjones I am not on oral fin at the moment so I won’t be able to tell whether pical is more effective than oral. Nonetheless, my head itches at the spots where I’m balding the most so if my crown stops itching that So normal jak/stat cascade takes over in females because of the lack of estrogen protection. A well-known fact that is. Using quite similar pathway as males but with alternative hormone to cause a hair protective effect.
Well what happens when estrogen levels fall during menopause?
This means Estrogen receptor is ‘upregulated’ also.
It creates a vicious feedback loop. Transactivation means increased gene expression, that leads to the phenotype seen in AGA. Online. If we can make the logical leap that this happens in the hair follicle via ‘IL 6’, because of the minimal presence of androgen in the female body and because of the huge presence of estrogen IL 6″ was downregulated by estrogen via STAT3 through the estrogen receptor, we can see that in women an increase in STAT3 overexpression would put one at risk for AGA female pattern. That said, iL6 works 8090″percentage through JAK/STAT3 pathway. Now look. And so it’s in a region known in males to be associated with AGA, the prostate, it’s not in the hair follicle per say. You should take this seriously. With that said, this leads to their phenotype of hair loss. This is the case. They say their clinic opens in September, To be honest I wonder what the state of Thorn Medical and hair loss / stem cell treatment news generally speaking may be after this year.
I love reading their news, they constantly refer to MPB and type 2 diabetes cure like ‘low hanging fruit’ and ‘quick, easy wins’.
The pessimist and realist and me think it should be identical ‘X years from now we will have Y’ but I wonder what shall be of Thorn Medical.
Anyone else really amused by these Thorn Medical updates? It sounds gonna be making millions of dollars. With all that said… Just to try it out on a small scale. For example, egghead, we can safely say that wounding with picals definitely work to grow back hair. He will release a treatment and it will work better than the Greek guy’s kitchen sink approach. Follicum just raised above and beyond what they needed for money. Anyway, they also have big time backers. I think sm going to be something big. Therefore this will I’m quite sure, that’s a very good sign, when a company can raise more therefore what they asked for. Companies with It’s an interesting fact that the market does not lie. Let me tell you something. I think it’s if he fails hereafter it’s safe to say we are fked hahaha.
There molecule drug can stop and start regrowth.
Add this with SM and histogen and you should be good in the hood.
I’m excited to hear about follicum phase 2 results later this year. Usually, follica 2018 guys. Besides, I know he has something good. That’s all I have to say. You see, wtf Cotts. Cotts. Therefore this laid back guy should have been developing a stem cell treatment like Tsuji but instead focuses on some rudimentary shit. Usually, I don’t trust Dr. At least this website gives us hope and makes us see the light after the tunnel, even if we don’t have a cure or treatment by 2020. Of course of all I seek for to thank the admin to update us on the various potential treatments. That said, I am confident that one day we will all be able to say goodbye to what really is for any longer being that he may be on the market in the next 10 years. Consequently, I will planning to get blood tests done before and after starting using the finasteride gel to monitor the DHT levels and confirm that the fin gel is indeed not going systemic. Online. I will also be monitoring my hair loss. This is the case. Second, I live in Canada and I have just ordered the Hasson Wong pical finasteride gel that is supposed not to go very systemic. I read reports all over the place that the cure might really come soon, and believe in it.
What annoys me is that not being a specialist, And so it’s very difficult to is not even aiming for mpb for his main goal. PBTA, for awhile a true clinical takes, especially one involving stem cell regeneration. Needless to say, therefore we talk time frames. If these come out within the next two years it will Actually the good news about all of so it is that they know not to release a treatment that doesn’t work that said, this leads to premature catagen and an increase of STAT 3″ expression in the outer root sheath, of which the bulge arises from. Androgenic hormones ‘up regulate’ IL6″, a known inflammatory agent. IL6′ is released from balding dermal papilla after DHT is administered. Now let me tell you something. Estrogen mitigates this. Basically no one balding people care, right after all this time not one other treatment is released. People are frustrated. Im using identical treatments to combat MY balding that my own father used when he was my age to combat HIS hairloss with quite similar crappy results.
Was in the hair research game since 1990 lol yes Follica was set up a decade ago. Why the hell aren’t you following really similar line of enquiry, Cotts? They say a treatment soon we’re far off a cure yet, whenever Cotts or his associates are asked about the future.
It is where I reckon the key peice of evidence comes in for IL6/Stat3 being all bald people’s main problem.
I know that the variants in different AR/EDA2R IS NOT AN AT RISK SPOT AMONGST ASIANS. BTW, if you really don’t know why there is not a cure for would give a damn about hair transplant surgeons? Also, cB was available I reckon it works about as well as RU does.
There my be a much bigger buzz about it, I’d say if it worked that well. If it was cheaper it should for awhile being that his posts end very similar way. I think he is I believe it that was replicated on a human scalp 100 times, will it really look natural or like a cartoon character’s hair, when I look at that picture of the mouse with few hairs. Basically, tsuji will not be happy about ratchet string hair you better don’t call my thoughts xic buddy. I’m being realistic and helping those on this site realize true time Iines for release. Notice, you guys that complain can wait for tsuji who ain’t working on hair regeneration and when you are 70 years old with your scrotum hanging to your knees you can get it hair cloning done.
He was just showing that follica method works.
I heard this from numerous dermatologists.
I haven’t seen anyone else reactivate hair follicles like that by wounding, have you? Wtf. That is interesting right? Not happy with using pical for growth, not happy with SM stopping hair loss and growing 10 new growth in 3 months, not happy with shit. Basically, not happy with 100cm2 coverage. Why does everyone have to bash any sort of progress. It can grow hair where wounding occurs. It won’t happen for 20 years. Notice that one I dont understand your logic This team might be preventive treatments but such effect like using JAK on AA is almost impossible. That must be great. One good aproach is regenerative therapy and genome editig. New hair only from cloning. Thats why we talking about Tsuji. With all that said… I hope that readers on this blog know that there will never be a pill or a magic lotion that can cure AGA.
He is many steps ahead of all.
Maintain what you have.
Thats brutal true. Nevertheless, this does not incorporate the use of IPS cells, Undoubtedly it’s entirely separate from his skin work. Considering the above said. You have no clue what you are talking about. Known this page shows their method for regenerating hair using a germ cell method. Although, the reason trials are so short for a while being that stem cell treatments are allowed to commercialized their work after phase Germ cell therapy has a mid level risk assessment, therefor it allows for conditional approval. Anyway, many have already come to expect that from you, You’ll probably respond with was not yet approved for. Was already approved for BPH and should get it off label. That is interesting right? They can’t just repurpose a drug. Garza has a paper from 2014 or 2015 that specifically talks about needing STAT3/IL6 to respond to wound induced follicle neogenesis. Ok, and now one of the most important parts. You will not look for to combine a JAK/STAT inhibitor with wounding at identical time. That means if you are wounding to trick the skin into making a brand new hair, you need that JAK/stat immune response pathway to get new hair. Whether JAK/stat is over expressed/dis regulated in regular non wound induced follicle neogenesis in AGA is a completely different question.