While stopping a certain medication can also cause hair loss in some, not in others. Certain genes make the p of the scalp more vulnerable to a male hormone, dihydrotestosterone or DHT, that shuts down follicles so they don’t produce new hairs.
Similar interplay of male hormones and heredity can cause a general thinning of hair in women.
Result is malepattern baldness, that starts with a receding hairline and bald spot. Remember, experiments are challenging the long held notion that new follicles are never formed in humans and that follicles can never be revived once they become inactive. For those hoping for a brand new technology that will carpet a bald scalp like Astroturf, top-notch shot may come from a small group of companies that are striving to cultivate new follicles like seedlings. In another approach, company scientists at Atlanta’s Aderans Research Institute are taking certain key cells from the scalp and making an attempt to multiply their numbers by growing them in culture.
Two cell types were chosen as long as they exchange chemical signals that foster follicle formation. Then the propagated cells could have been injected into the scalp as hair seeds to create new follicles, if the method works. Half the population, both male and female, see their locks thinning by age 50 -and many can’t take the loss lightly, Mirmirani said. Some may feel sheepish raising the question, given the weightier problems needing a scientific fix. Hair loss ain’t a ‘lifethreatening’ condition, concedes Kaiser Permanente dermatologist Paradi Mirmirani. It’s not even clear why humans, over the course of evolution, shed quite a few their thicker body hair but kept a crop on the head. Fact, much is still unknown about the phenomenon of balding, a trait that only humans and the uncertain part is AndroScience Corp. San Diego, that is developing a drug that degrades the cell receptors for DHT. Drugs for balding, however, usually work only on follicles that are still active.
Other companies are trying variations of this method.
Washenik said he once predicted a treatment will be ready in five years.
Now in my opinion it’s better not to make an estimate as long as I’m really not sure, he said. Cotsarelis theorized that the healing process created a window of time when new skin structures could form. However, a pilot study in humans is planned within a few months using a strategy outlined in May by Dr. George Cotsarelis, a University of Pennsylvania dermatology professor who discovered that mice healing from wounds could produce hair follicles. Basically, that passionate attachment is helping to speed research on new treatments being that investors see a potential gold mine in the field.
Plenty of people will pay out of their own pockets even if the cost is a bit hairraising, most health plans don’t reimburse for antibalding drugs or transplants.
They’re throwing an arsenal of hightech ols at the condition.
That explains why a small but determined bunch of companies and academics are mining the hair shaft for clues to the molecular mechanisms of balding. Needless to say, ltd, the world’s largest wigmaker, and its affiliate Bosley, a major hair transplant company. Ken Washenik. Generally, no hairs or follicles are produced in the culturing step, said Aderans executive Dr, the tactic is often called hair cloning. Research is a project of Aderans Co. Hair transplant’ surgeons take follicles from the back and sides of the head, that seem immune to the balding effects of male hormones, and move them to the crown. Now regarding the aforementioned fact… I’m sure that the success of transplants has always been limited, however, by the finite percentage of hair a patient still has left to move around.
Will they have the decadeslong lifespan of a baby’s follicles, or will they quickly succumb to the male hormones that caused the baldness in the first instance, So in case new follicles form on p of a bald scalp. That’s a question raised by Chris Ehrlich, a partner in the Menlo Park VC firm InterWest Partners, that has helped fund Follica. Besides, the Boston company he ‘cofounded’, Follica Inc, is attempting to duplicate the regenerative environment of wound healing in humans by using a modified sort of microdermabrasion, a kind of skin treatment that grinds off dead surface skin cells and encourages repair by deeper cells. You see, for a minority of balding people, episodes of hair loss stem from diseases similar to skin infections and overall health disorders, or stresses just like surgery and childbirth. Treatments for such hair loss are often geared to fix the underlying cause. Only two drugs are approved by the Food and Drug Administration to treat common baldness -Merck’s Propecia and Johnson’s Rogaine.